Good for the Heart

 There is ongoing research into the effect of anthocyanin on blood pressure.

 

One of the many studies in this field shows an inverse relationship between high intake of anthocyanin with lower arterial stiffness (1), other shows a high intake of anthocyanins may reduce myocardial infarction (MI) risk in predominantly young women (2) as well as higher intakes of fruit-based flavonoids were associated with a lower risk of nonfatal MI and ischemic stroke in men (3).  

 

Although more intervention trials are needed to further examine the health impact of increasing intakes of commonly consumed anthocyanin-rich foods there is promising outcomes: One is the discovery that the potential health benefit of blueberries may be due to the vascular effects of anthocyanins that predominantly circulate in blood as phenolic acid metabolites (4). Results on Haskap intervention revealed that both diastolic blood pressure and heart rate were significantly lower following the 400 mg dose when compared to the control (5)

(1)    Amy Jennings, Ailsa A Welch, Sue J Fairweather-Tait, Colin Kay, Anne-Marie Minihane, Phil Chowienczyk, Benyu Jiang, Marina Cecelja, Tim Spector, Alex Macgregor, Aedín Cassidy, Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women, The American Journal of Clinical Nutrition, Volume 96, Issue 4, October 2012, Pages 781–788, https://doi.org/10.3945/ajcn.112.042036

(2)    Cassidy, Aedín et al. “High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women.” Circulation vol. 127,2 (2013): 188-96. doi:10.1161/CIRCULATIONAHA.112.122408 https://pubmed.ncbi.nlm.nih.gov/23319811/                           

(3)   Cassidy, Aedín et al. “Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men.” The American journal of clinical nutrition vol. 104,3 (2016): 587-94. doi:10.3945/ajcn.116.133132 https://pubmed.ncbi.nlm.nih.gov/27488237/    

         

(4)    Ana Rodriguez-Mateos, PhD, Geoffrey Istas, MSc, Lisa Boschek, MD, Rodrigo P Feliciano, PhD, Charlotte E Mills, PhD, Céline Boby, PhD, Sergio Gomez-Alonso, PhD, Dragan Milenkovic, PhD, Christian Heiss, MD, Circulating Anthocyanin Metabolites Mediate Vascular Benefits of Blueberries: Insights From Randomized Controlled Trials, Metabolomics, and Nutrigenomics, The Journals of Gerontology: Series A, Volume 74, Issue 7, July 2019, Pages 967–976, https://doi.org/10.1093/gerona/glz047

(5)    Bell, L., Williams, C.M. A pilot dose–response study of the acute effects of haskap berry extract (Lonicera caerulea L.) on cognition, mood, and blood pressure in older adults. Eur J Nutr 58, 3325–3334 (2019). https://doi.org/10.1007/s00394-018-1877-9

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